Nick Kroll

Nick Birch / Maury the Hormone Monster / Coach Steve / Lola Skumpy / Rick the Hormone Monster (voice)

John Mulaney

Andrew Glouberman (voice)

Jessi Klein

Jessi Glaser (voice)

Jason Mantzoukas

Jay Bilzerian (voice)

Maya Rudolph

Diane Birch / Connie the Hormone Monstress (voice)

Fred Armisen

Elliot Birch (voice)

Jordan Peele

Ghost of Duke Ellington (voice)

Andrew Rannells

Leander / Matthew MacDell (voice)

Jenny Slate

Missy Foreman-Greenwald (voice)

Joe Wengert

Caleb / Lump Humpman (voice)

Ayo Edebiri

Missy Foreman-Greenwald (voice)

June Diane Raphael

Richard Kind

Paula Pell

Neil Casey

Detective Dumont / Lars (voice)

Jessica Chaffin

Shannon Glaser / Grace / Intellect Sphinx (voice)

Jon Daly

Jak Knight

DeVon / Gina's Brother #2 (voice)

Chelsea Peretti

Diaphragm (voice)

Seth Morris

Greg Glaser (voice)

Mark Rivers

(voice)

Gil Ozeri

Jew Fishman (voice)

Nathan Fillion

Nathan Fillion (voice)

Kat Dennings

Leah Birch / Lorraine the Hormone Monstress (voice)

Gina Rodriguez

Gina Alvarez / Gina Parrot (voice)

David Thewlis

Lionel St. Swithens (voice)

Thandiwe Newton

Heather Lawless

Jenna Bilzerian (voice)

Maria Bamford

Brandon Kyle Goodman

Walter (voice)

Nick Kroll

Yaratıcı

Mark Levin

Yaratıcı, Yazar

Jennifer Flackett

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Andrew Goldberg

Yaratıcı

Bryan Francis

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Joel Moser

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Henrique Jardim

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Bob Suarez

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Andres Salaff

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Alex Salyer

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Mike L. Mayfield

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Paul Scarlata

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Kim Arndt

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Dave Stone

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Chris Ybarra

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Ross Bradley

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